In early 2002, Ross designed the promotional poster for the 2002 Academy Awards, which depicted Oscar perched atop the First National Building. The Academy loaned Ross an actual Oscar statuette for a week for him to use as reference for the painting. Ross stated that he photographed members of his family as if they were receiving it. That same year, he was one of four artists who depicted Spider-Man on one of the covers to the April 27, 2002, issue of TV Guide as a promotional tie-in to the feature film Spider-Man.

In 2004, DC compiled the coffee table book Mythology: The DC Comics Art of Alex Ross, written and designed by Chip Kidd. In late 2005, a paperback version of the book was published to include new artwork by Ross, including sketches for his Justice mini-series.

Also in 2004, Ross designed 15 paintings for the opening credits of the film Spider-Man 2. The paintings presented key elements from the first film. Ross later donated the paintings to be auctioned off on eBay to benefit the United Cancer Front.

In August 2005, Ross worked again with writer Jim Krueger and penciller Doug Braithwaite on 12-issue, bi-monthly limited series Justice for DC Comics. The series focuses on the enemies of the Justice League of America banding together to in an effort to defeat them.

After Justice he started on projects focusing on Golden Age characters: Project Superpowers with Jim Krueger for Dynamite Entertainment. and in 2008, Ross began work on Avengers/Invaders featuring Marvel characters but published by Dynamite Entertainment. The story pits World War II versions of Captain America, Namor, and other classic war characters against the modern Avengers groups. He has not stated what will happen in the series, but he has stated the recent death of Captain America has improved the story, since it was conceived a year before his death. He also collaborates on DC's Justice Society of America. Ross is also set to draw the covers of Dynamite Entertainment's comic book series featuring The Phantom. He will also redesign the hero's costume. In 2009 he was announced as cover artist for Fighting American.

Ross will be teamed with Kurt Busiek on Dynamite Entertainment's Kirby: Genesis, an eight-issue miniseries set to debut in the first quarter of 2011. The series, which will be their first full collaboration since Marvels 17 years previous, will feature a large group of Jack Kirby's creator-owned characters, the rights to which were acquired by Dynamite, such as Silver Star, Captain Victory, Galaxy Green, Tiger 21 and the Ninth Men. Ross will co-plot the book, handle designs, and will oversee the book overall with Busiek, who will script the series.

Ross' painted art includes:

(covers and interiors, except where noted):

DC Direct (the exclusive collectibles division of DC Comics) has produced 3 sets of action figures from the comic book Kingdom Come based on Alex Ross' artwork. The first set of figures included Superman, Wonder Woman, Green Lantern, and Hawkman. The second set included Batman, Red Robin, Captain Marvel, and Kid Flash. The last set included Magog, Flash, Armored Wonder Woman, and Deadman. An exclusive figure of Red Arrow was released through ToyFare magazine. DC Direct also released several other Ross-designed characters through their Elseworlds toylines. These figures included The Spectre, Norman McCay, Jade, Nightstar, Aquaman, and Blue Beetle. Ross designed the costume the current incarnation of Batwoman wears; this character has been released in action-figure form by DC Direct as part of its "52" line of toys.